“Objective: To evaluate the effectiveness of low-intensity laser therapy (LBI) in the healing of surgical wounds in newborns undergoing surgical correction of gastroschisis (G), omphalocele (O), anorectal anomaly (AA), inguinal hernia (HI), atresia of esophagus (EA), intestinal atresias (IA) and diaphragmatic event (DE). Methods: This is a quasi-experimental study carried out in a Neonatal Intensive Care Unit (UTIN) of a reference hospital of the health department of the Federal District (SES/DF). Low-intensity laser therapy (LBI) was used as a treatment for surgical wounds (FO) of newborns (NBs) who underwent elective or emergent surgeries, to correct congenital problems with high neonatal morbidity and mortality. This study was submitted to the research ethics committee of the University of Brasília (UnB) under the substantiated opinion CAEE 57349722.3.3001.5553. Results: The use of LBI produced important biostimulatory effects, acting directly on the reduction of edema, hyperemia and FO exudate. It was identified that the application does not have a homogeneous pattern throughout the treatment, with doses being manipulated according to the response of technical parts of each surgery. The dosage used was 0.2 cells per point of application and did not cause harmful effects, did not alter the physiological structure of the FO, medications in systemic circulation and specific parameters, with no adverse solutions to the treatment being identified. The surgical groups with the highest average doses and treatment time were AA and D, justified by FO dehiscence generated by fecal contamination, poor adhesion of the ostomy bag, friction and little change in position. On the other hand, the times with the lowest reduction in days and doses required were, respectively, HI, AE, ED, AI groups that did not suffer dehiscence. Conclusion: Therefore, the application of LBI to date has not caused harm or adverse events to newborns, consisting of a safe dose for all surgeries performed. However, the risks of adverse reactions, although minimal, should not be discarded in the population of the study and according to some authors it is believed that the greatest risk is hypersensitivity to non-ionizing radiation. Among the benefits identified are: reduction of edema, hyperemia, inflammatory process, exudate and dehiscence, consequently avoiding surgical procedures and loss of hospitalization time in the UTIN, considering that the healing time of the FO is the fastest and most effective instructions. more humanized, without methods that involve or affect newborns, making it an ideal adjuvant treatment and enhancer to routine conventional treatment in the UTIN.

“Introduction: Neurogenic bowel dysfunction affects most individuals with SB, leading to constipation and fecal incontinence (FI). Its negative impact on the health and quality of life (QoL) of the pediatric SB population is undeniable. Transanal irrigation (TAI) is a high-adherence, safe, and effective strategy to enable regular evacuations, improve constipation, and promote social fecal continence. There is a shortage of studies on TAI in the Brazilian pediatric population, and most have a qualitative approach. Objective: To investigate the functional and QoL outcomes in children and adolescents with SB attended in the Neurogenic Bowel (NB) Outpatient Care of the SARAH Rehabilitation Hospitals Network, Lago Norte Unit, and to analyze the results found through the Symptom Management Theory. Method: Converging mixed methods study. Data collection took place from March to July 2023, with the pediatric SB population attended in the units at Brasília and/or Lago Norte in the SARAH network. Data analysis took place in three stages: qualitative analysis, using Braun and Clarke's Reflexive Thematic Analysis (2006); a quantitative stage, in the form of a cross-sectional study with descriptive and inferential statistical analyses; and, finally, a mixed-methods data analysis, in which data was integrated using triangulation and side-by-side display. The theoretical framework was based on Symptom Management Theory, which was used to structure the data collection and analysis instrument, its dimensions (experience of symptoms, management strategies, and results), and nursing domains (personal, environmental, health and illness). Qualitative data were collected in interviews and quantitative data using a semistructure questionnaire, the Bristol Scale, Wexner's Index, and the Health-Related Quality of Life Scale (HRQoLS), the QUALAS-C (children), and the QUALAS-T (teens). The study included 109 children and their tutors, trained to carry out the TAI from March 2019 to January 2023, monitored by the NB outpatient team. The qualitative sample included 27 family caregivers. Results: The adherence rate was 91.7%. FI decreased in 90.7% of cases; 74% reached social fecal continence, and 76% showed improvements in constipation. The TAI allowed for scheduled evacuations, which was perceived by caregivers as bowel control (75.5%) and reflected feelings of normal bowel functioning. Participation in social school activities, leisure, and interpersonal relations was improved. Both aspects of the study showed high satisfaction of family caregivers (97%) and children (93.4%) with bowel management, associated to feelings of freedom, relief, and achievement. The qualitative portion of the study showed impact on self-esteem, less suffering, and the perception of more safety and tranquility. The use of the TAI had a positive impact on HRQoL, with cases with less FI and constipation showing a higher score at the QUALAS-T, as reported by the interviewees. Conclusions: The TAI is an effective, safe, and well-accepted strategy to control bowel eliminations, reduce constipation, reach social continence, and improve social participation, with a high degree of satisfaction and HRQoL improvement.”

“Introduction: Radiation Recall Dermatitis (RRD) is a rare and not fully understood phenomenon observed in patients undergoing radiotherapy. Objective: To map the evidence related to RRD in breast cancer patients previously undergoing radiotherapy. Methods: Scoping review following the JBI Collaboration methodology. The research question was formulated with the PCC strategy: Patient (breast cancer patients previously undergoing radiotherapy), Concept (RRD), and Context (exposure to a specific agent with the development of a reaction). The main electronic and grey literature databases were Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences, PubMed, Scopus, Web of Science Core Collection (WoSCC), Google Scholar, and ProQuestTM Dissertation & Theses Citation Index. Studies published in any language, without restriction on publication year, were included. Results: 87 primary studies and 10 secondary studies were included. The primary studies consisted of 81 case reports, six cohort studies, four case series, and two clinical trials, totaling 102 described cases. The majority of RRD cases were associated with the use of antineoplastics (77.45%), either alone or in combination, such as chemotherapy, targeted therapy, immunotherapy, and/or hormone therapy. Among the types of agents causing RRD, whether antineoplastic or not, isolated chemotherapy (47.05%) was the most evident in the reported cases. Docetaxel-based protocols (16.66%) stood out in terms of case numbers, totaling 17 cases. The time interval between Docetaxel administration and RRD ranged from 2 to approximately 180 days. The minority of RRD cases were associated with non-antineoplastics (17.64%), such as antimicrobials, vaccines, COVID-19 infection, radiopharmaceuticals, sunlight, antihypertensives, statins, anesthetics, antidepressants, and herbalbased ointments. It is noteworthy the significant number of RRD cases associated with the use of COVID-19 vaccines, considering that these vaccines began to be introduced into the global scenario by the end of 2020 and totaled seven cases (6.86%). Conclusion: Antineoplastic agents represent the primary therapeutic approach for breast cancer patients. RRD may result in erythema, desquamation, edema, pruritus, pain, urticaria, vesicles, necrosis, ulceration, and hemorrhage, which can compromise the quality of life for these patients. Understanding the incidence, etiologic, and predictive factors for developing RRD is crucial for planning its management.

"Objective: To describe the process of development and validation of an instructional design for a standard virtual urotherapy program aimed at families, with the aim of helping to manage urinary and intestinal symptoms in children and adolescents. Method: This is a methodological research, with a view to the development and validation of instructional design - a digital educational technology for families of children and adolescents with urinary and intestinal symptoms, covering the five components of urotherapy proposed standard by the ICCS (International Children's Continence Society). The study will cover the phases of the ADDIE Model instructional design process proposed by Filatro (2019). The last phase associated with the evaluation applied to the internal validation phase of the technology to be carried out with the presentation of the final version of the instructional design to judges, specialists in care in the area of pediatric urology and stomatherapy. Expected Results: It is expected to develop an instructional design for a virtual urotherapy program aimed at families of children and adolescents with urinary and intestinal symptoms, in order to provide an online and asynchronous tool to support self-care through instruction for family members."

“Introduction: Technology-dependent children are those considered clinically fragile and socially vulnerable, who need some technological device to compensate for the loss of a vital function of the body. In this context, family members need to continuously monitor them full-time, including during hospitalization, which has an impact on family functioning, especially on the life of the person who assumes the role of primary caregiver. Objective: To know the profile of technology-dependent children in a Pediatric Intensive Care Unit and the repercussions of prolonged hospitalization on family life. Methodology: This is a quantitative and qualitative research, carried out in a public Pediatric Intensive Care Unit in the Federal District. For the collection of quantitative data, two instruments were used, a structured questionnaire with open and closed questions, prepared by the researcher and the abbreviated The World Health Organization Quality of Life, and in the qualitative stage, an open in-depth interview was used. For quantitative data analysis, descriptive statistics, frequency distribution and application of tests such as Spearman Correlation, Kruskal-Wallis and Mann-Whitney were performed. For qualitative data, the thematic content analysis proposed by Minayo was used. Results: 21 technology-dependent children and their respective main caregivers participated in the study. All participated in the quantitative stage and, of these, 11 in the qualitative stage. Clinical aspects revealed children with prolonged hospitalization time, most with encephalopathy and using multiple devices. Social data show the mother as the main caregiver, with a medium level of education, unemployed and with low income. The damage to the mothers' quality of life is highlighted, with more accentuated rates in the social and environmental domains, directly influenced by schooling and income. The qualitative results highlight the mothers' negative feelings, the change in family routine and the precarious support network. Conclusion: The study reveals data of epidemiological and social importance, as the vulnerability of technologydependent children and their families is perceived in several aspects, which is enhanced in the context of prolonged hospitalization.”

"Introduction: The relationship between nurse and patient is still mostly paternalistic. In this context, the patient's autonomy is compromised in terms of decision-making regarding the body and health. Objective: To analyze the nurse-patient relationship, the implications for clinical practice, the quality of care provided and the decision-making capacity of patients in a clinical unit of a hospital in the public health network of the Federal District. Method: A qualitative and documentary research was carried out. Through interviews with nurses and collection of information from clinical records. Result: In the interviews, most nurses reported that the patients' decisions were respected by them as professionals, while the nursing records only showed information about clinical demands and a brief description of the procedures performed. Few records highlighted the issue of patient and family guidance by the nurse, the informed consent process and the right to choose were practically not addressed. Conclusion: The evidence found in this study indicated that nurses, although they had a respectful attitude,did not develop an action of respect for the patient's autonomy. They did not respect the patient's rights as they did not enable them to act autonomously, resulting in unethical and humane nursing care."

"Hand-foot syndrome (HPS), recently included in the erythema toxicum group of chemotherapy syndromes, is a common toxicity in patients undergoing chemotherapy, with an incidence ranging from 2% to 60%. It is initially characterized by paresthesia that can progress to burning pain, edema, erythema and even desquamation of the palms and soles. In more severe cases, bullous plaques may form. Depending on the severity, SMP can lead to discontinuation of the antineoplastic agent, decreased quality of life, as well as impairment of the patient's performance in their daily activities. However, although the occurrence of SMP is frequent with the use of some antineoplastic agents, its pathogenesis has not yet been fully elucidated. Regarding the prevention of SMP, it is observed that several topical and parenteral interventions have been analyzed, however, current studies do not allow understanding the range of interventions available for the prevention of SMP. Thus, this study aimed to map the topical interventions used for the prevention of SMP in cancer patients undergoing chemotherapy/targeted therapy. This review was written in accordance with the recommendations of the PRISMA-ScR (extension to Scope Review) and the Joanna Briggs Institute Manual. Searches were performed in CINAHL, Cochrane CENTRAL, EMBASE, LILACS, LIVIVO, PubMed, Scopus, and Web of Science electronic databases. Gray literature was accessed through Google Scholar and Pro-Quest, in addition to additional searches of the reference lists of included studies. The searches resulted in 12,016 references and the final sample consisted of 45 studies. Of the 45 studies surveyed, 44% of them were randomized clinical trials (RCTs), and of these RCTs, 30% evaluated the use of herbal medicines and 25% evaluated the use of urea. It was also observed that the studies included in this review were published in the last 20 years, ranging from 2004 to 2023, with a higher prevalence in the year 2022. Regarding the region of origin of the studies, there was a slight higher volume of publications in western countries, with 51% of the studies carried out in this region. Of the mentioned cancers, 36% were of the colon and rectum followed by 20% of the breast. As for the type of chemotherapy, 71% of the studies that cited anticancer protocols cited capecitabine. With regard to the SMP rating scales, of the studies that cited any, 59% used the CTCAE. Of the total interventions mapped, 42 topical interventions were identified for the prevention of hand-foot syndrome, among them: moisturizing creams, corticosteroids, acids, mapisal, silymarin and henna. However, urea was the most cited intervention (62%). As for the presentations of the interventions, these ranged from creams, ointments, gels, hydrocolloids, decoctions, patches, powders, oils and soaps. In short, the results enabled a review of topical interventions, with emphasis on the use of urea and moisturizing creams as the most studied interventions. This study can help researchers to identify interventions that can be evaluated for the prevention of SMP, to avoid the reproduction of studies that evaluate interventions that already have their effect well elucidated in the literature."

“Lower Urinary Tract Symptoms (LUTS) are characterized by changes in bladder dynamics, whether in the filling phase or during urinary elimination. These LUTS, including urinary urgency, urinary Frequency and related discomfort, with or without incontinence, are presente in manu people’s lives. There ir a general consensus among health professionals, and some communities, that it is recommended to reduce the consuption of some foods considered potentially irritating to the bladder in the diet of people with LUTS, such as coffee, tea, alccohol, carbonates drinks and sweeteners. These are divides into four categories, namely: caffeinated 9coffee and tea), citrus (fruits and citrus-based drinks), carbonated (carbonated drinks) and chocolate (chocolates). Therefore, the following question arises. “What are the potentially vesical irritating food and the impacts caused by their consumption in people with lower urinary tract symptoms (LUTS)?”. For the methogology, two Search strategies were created, using the PCC, directed to the general public and the second Search strategy to the pediatric public. Article searches were carried out in large databases such as CINAHL, PUBMED, Cochrane Central, LILACS, SCOPUS, Web of Science and in the gray literatura: SCI-HUB. Two reviewers were responsible for stratifying the articles and Reading them in full. 1657 articles were found. After Reading the abstracts, 31 articles were selected to be read in full and the final sample consisted of 23 articles. It was obtained as a result that caffeine appears in the literatura as a potentially irritating food for the bladder, influenced by the amount of daily doses ingested and the concentration, since the other potentially irritating foods for the bladder were not found in articles that provide scientific basis. This study pavês the way for new experimental studies, to arrive at the conclusion of which are the foods that are potentially irritating to the bladder and what are their interferences in the urinary bladder. More studies are needed to reach a conclusion."

“Introduction: The understand the concept of health is an ongoing and relevant concern, especially in the context of the of immigration, due to cultural differences between countries. The objective of this study was to understand the meanings of health for immigrants in the Federal District. Method: The present search is an exploratory study with a qualitative approach, involving seven immigrant participants aged 18 years or older, enrolled in a Portuguese language course for at least three months or possessing proficiency in the Portuguese language, as well as having internet access through an electronic device. The information was collected through digital interviews conducted between December 2022 and April 2023, after participants consented to participate in the research by signing the informed consent form and the image use agreement. During the interviews, a semistructured questionnaire was used with the guiding question: "What does it mean healthy for you?" The interviews lasted a total of 146 minutes, with an average time of 20.8 minutes per participant. The dialogs was transcribed in full and organized in Excel, and after organization, the dialogs was analyzed using content analysis. Results and Discussion: Four men and three women participated in this study. The interviewees originated from North America, South America, Asia, Africa and India. After organizing the data extracted from the interviews and conducting a thorough analysis, the following categories were identified: "nationality, religion, and language", "healthcare services and comorbidities for immigrants", "dietary and lifestyle habits in the destination country", "feelings about immigration", "living conditions and immigration", "impact of immigration on social and family networks" and "work and purchasing power for immigrants in the destination country". It was observed that cultural differences can influence perceptions of illness, the pursuit of medical treatment, and self-care practices, resulting in different meanings of what constitutes health. Conclusion: Nationality and cultural habits of immigrants have a significant impact on their understanding of health and how they take care of their health, especially when confronted with the need to adapt to a new country where social determinants of health influence their lives differently. It is crucial to consider these cultural differences and promote sensitive and culturally appropriate approaches in healthcare services to meet the specific needs of immigrants.”

“Objective: To know the magnitude of the occurrence of maternal deaths in the Federal District in the period from 2012 to 2021. Method: This is a study with a mixed, qualitative and quantitative approach of the descriptive type. The use of this type of research is justified by the need to explore official documents in the search for evidence of maternal health policies launched, as well as to collect data on maternal mortality. Results and Discussion: Data provided by the Ministry of Health indicate that the Maternal Mortality (MM) indicators declined from 2012 to 2019, probably as a result of Health Policies. Although there have been advances in MM indicators, the high mortality ratios in the DF after the onset of the Covid-19 pandemic represent a setback and exceed coefficients recorded 25 years ago. Final considerations: The Policies and guidelines released provided an important contribution to the progress of women's health. But even so, some goals remain pending, especially those related to the reduction of the MM. In this sense, the importance of ensuring access and quality assistance to pregnant, parturient and postpartum women is reinforced, since MM represents a major social problem, at a time when the Covid-19 pandemic threatens the lives of these groups. populations that are part of the reproduction and maintenance of humanity”.

“Introduction: Every blood transfusion involves risks. The transfusion process involves several substeps that need care to ensure patient safety. Studies report failures by professionals in checking the medical prescription of blood components, identifying the patient and blood samples, checking all data on the bag labels, inappropriate conduct in the face of transfusion reactions, patient monitoring, recording and documentation of the entire process. Such failures can cause serious incidents such as incompatible transfusions, incorrect blood component transfusions or non-observance of transfusion reactions and related care. Objective: To analyze patient safety incidents related to the blood transfusion process in a university hospital. Methods: Quantitative study, with cross-sectional design, developed in a university hospital in the Midwest. The study settings were the Medical Clinic and the Transplant Unit, including all transfusions performed between March 2021 and March 2022. Data were collected from the analysis of the blood components request form, blood transfusion prescription, monitoring of vital signs, post-transfusion guest book, patient chart, recipient's file and computerized system of the blood center. Descriptive analysis was performed using frequencies and percentages for categorical variables and measures of central tendency and dispersion for continuous variables. Results: 509 transfusions were analyzed, noting the occurrence of 1,629 incidents. Of these, 904 (55.49%) were related to documentation and 725 (44.5%) to blood components. Only 22 (4.3%) transfusions did not present any type of incident, estimating a prevalence of 95.5% (95% CI 93.6%-97.2%). Among the incidents related to documentation, the following problems were verified: ambiguous / illegible / incomplete / incorrect / erased / missing information (771), lack of verification of the medical prescription (146), contraindication (1), missing/unavailable document (133). As for the incidents related to the use of blood/blood component, it was found the occurrence of adverse effect (2), vital signs not verified (251), wrong blood component (39), absence of post-transfusion follow-up (285), wrong speed (1). Fourteen transfusion reactions were identified, of which six were not notified by the sector to the responsible body, four bags were not returned to the Transfusion Agency and post-transfusion samples were not collected, five did not perform a blood culture on the bag. Conclusion: The transfusion process involves several steps and the high incidence of non-conformities highlights the urgent need to review the work process to make the practice safer. The indicators raised point to the need for organizational interventions to remedy the identified problems and it is expected to contribute to the elaboration of health policies and/or protocols that make the blood transfusion process safer.”

"Introduction: Entrepreneurship is a phenomenon that has been studied for many decades and originated with economic thinkers in the 18th and 19th centuries. Over the years, the term has been capitalized for different areas of knowledge, making it polysemic and multidisciplinary. In the context of health, entrepreneurship has generally been understood from the perspective of a niche market with a profitable bias, as a proposal for innovative solutions to improve the quality of care in health organizations, and also with a focus on transformation and social impact. However, it is observed that, eventually, the specificities of the health system, as well as professional training in health, have not been considered in the application of entrepreneurship in the national health scenario. In view of this, this study aimed to analyze the concept of health entrepreneurship; and to identify its attributes, antecedents and consequents in the context of health in Brazil, as well as its substitute terms, related concepts and applications. Method: This is a concept analysis study, under Rodgers' evolutionary view. To identify the sources of evidence, a scoping review was conducted, according to the methodology proposed by the Joanna Briggs Institute, in the following databases: National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature and Latin American and Caribbean Health Sciences Literature. Results: Considering the eligibility criteria, 20 sources of evidence were included. Of this total, 65.0% were published in the last 5 years, and the qualitative exploratory-descriptive design was the most frequent (35.0%). Regarding the research setting, there was a predominance of Higher Education institutions (35.0%), and half of the studies occurred in the southern region of Brazil. We identified entrepreneurship concepts authored by the authors of the sources of evidence, and others were referenced from previous studies, including international literature. In the concept analysis, the main descriptors referring to the attributes, antecedents and consequents of the concepts of health entrepreneurship, nursing entrepreneurship, medical entrepreneurship and other three types of entrepreneurship (social, business/entrepreneurship and intrapreneurship) were evidenced. As for the other aspects of the concept analysis, among the 20 articles included in the sample, 17 (85.0%) presented substitute terms. Regarding the concepts related to entrepreneurship, most refer to the characteristics necessary for its development. And finally, a wide scope of application of the concept was identified, with emphasis on university hospitals. Conclusion: In general, the concept of health entrepreneurship in the Brazilian context has been influenced by different researchers from different areas of knowledge, including international literature, which presupposes the importance of considering sociocultural and temporal variations in order to adapt its application according to the specificities of each context. Therefore, it is expected, from these findings, to incite reflections and discussions about the application and incorporation of the concept of entrepreneurship and its different typologies in the Brazilian health context; contributing to expand its reach as a potentializing tool for both the health profession and the health system."

“Objective: To clearly outline the factors related to primary care that interfere in hospitalizations due to conditions sensitive to primary care. Method: This is a Scoping Review, as per the methodological proposal of the Joanna Briggs Institute (JBI), which is reported according to the standards set by the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist. Results: 2.806 articles were identified. Of these, 186 were included in this study. The primary care user population factors were described as per biological, clinical, behavioral, and socio-economical domains. Among the main prejudicial factors that favored the occurrence of hospitalizations were age extremes, male sex, black ethnicity, comorbidities, substance dependence or addiction, incomplete vaccination, limitation of daily life activities, single marital status, low educational level, rurality, immigrant status, and lower income level. The following contextual factor domains deserve highlight: the health team, access, longitudinality, and care coordination; family health coverage strategy; health unit structural aspects; hospital features; and health programs and policies. Conclusion: The senstive hospitalization index shall be utilized to survey health services considering protective and prejudicial aspects of both intrinsical and underlying user factors, as well as structural, organizational, and strategic factors regarding primary health care.”

Introduction: The National Immunization Program (PNI) has great relevance for the health of the population, as it enables the distribution and expansion of access to immunization agents, especially for those distributed in early childhood. With the advent of Covid 19, the most urgent health needs were prioritized to the detriment of other services that were interrupted, leaving the child population uncovered and exposed to falling ill from vaccine-preventable diseases. Objective: describe the vaccination status of children in the first year of life and the main factors involved from the parents’ perspective. Methodology: This is a cross-sectional, descriptive, retrospective study, with a quantitative and qualitative approach, carried out in 03 Basic Health Units in the Southern Health Region of the Federal District. The sample consisted of children under one year of age and their parents or legal guardians. The "Data collection instrument on factors related to vaccine delays", developed by the author, adapted from Garcia (2022), was applied. The instrument developed is mixed (quantitative and qualitative), and was answered by the parent and/or guardian, with questions that assess family members' knowledge about vaccines, vaccination delays and the child's health situation. In the quantitative analysis, the data were entered into an Excel spreadsheet and analyzed using the Statistical Package for the Social Science (SPSS) software, where the prevalence of each delayed dose was estimated. For the analysis of qualitative data, the Bardin Content Analysis technique was carried out, where the interviewees' audios were transcribed, after answering the semi-structured interview (chosen document). Thus, after formulating the objectives, hypotheses were raised about possible categories that could collaborate with the development of the research. Results and Discussion: vaccination records of 32 children were analyzed. The average age range was 1.6 years old. In total, 127 vaccination delays were identified, the most prevalent being: 1st Meningococcal booster dose; 2nd Hepatitis B; and 3rd VIP and Pentavalent, both third doses. Conclusion: Factors such as social isolation, adverse effects of vaccines, anti-vaccine movements, lack of knowledge about vaccines were cited as possible causes for vaccine hesitancy. The main limitation of the study was to ensure a more robust sample for better analysis. This limitation occurred due to the Ministry of Health program (Previne Brasil) which, through the launch of goals as a strategy to mitigate the damage occurred during the pandemic, encouraged the updating of vaccination records for children under 1 year of age, which had an impact on the process of data collection, since many of the booklets evaluated had already been completely updated. more in-depth studies on the impact of the pandemic on child health are encouraged, especially with regard to the field of immunization, since an unvaccinated population is subject to being infected by previously eradicated diseases, considerably affecting the country's public health.

"INTRODUCTION: It is estimated that, worldwide, 57 million people need palliative care, and of these, only 16% receive it. The quality of death is closely linked with the provision of palliative care to the population in need. The result of this situation is an incalculable excess of suffering, not only for those who are about to die, but also for their loved ones. Caring for a good death means, above all, promoting comfort, which is the result of health care practices, reconciling rationality and sensitivity, ensuring the dignity of the patient and his family. In this sense, knowing the comfort experiences of patients becomes a relevant aspect for the practice of care, in order to guide the care provided according to the needs of patients, maximizing the effect of comfort interventions. The study aims to answer the following guiding question: Do patients in palliative care have their comfort needs covered during palliative care? OBJECTIVE: to analyze the comfort experience of patients in palliative care in the light of Katharine Kolcaba's Theory of Comfort. METHOD: This is an exploratory, descriptive research, based on a qualitative approach, interpreted in the light of the Theory of Comfort, by Katharine Kolcaba. The study was carried out with patients in palliative care followed in two public hospitals in the Federal District. Two instruments were used for data collection: a sociodemographic questionnaire and a semi-structured interview script, based on Katharine Kolcaba's Theory. Data collection took place in the period between December 2020 and December 2022. The corpus of the interviews was subjected to content analysis with the aid of the IRAMUTEQ software. RESULTS AND DISCUSSION: Eight patients (hospital A) and nine patients (hospital B) in palliative care participated in the study. The interviews carried out with the participants were transcribed and subjected to content analysis. The general corpus of Hospital A was categorized into two axes and six classes. Axis one was named “Discomfort in falling ill”, consisting of class 3 “stimulus situations” and class 4 “health care needs”, which is related to the moment of diagnosis about the disease, metastasis and PC and its physical/emotional consequences , that is, the history of the disease. Axis 2 was called “Discomfort in living and dying” formed by classes 1 “multidimensionality of comfort”, class 2 “family support”, class 5 “dying process and current experiences” and class 6 “life history and past experiences”, mentions the different situations regarding comfort and discomfort involving the promoting sources, the life history of each one and the process of dying. The general corpus of Hospital B was categorized into two axes and six classes. Axis 1 is composed of a class named “stimulus situation”, which is related to the speed with which the individual discovered the new condition and their health-seeking behaviors. Axis 2 was called “Alpha Pressure”, formed by class 2 “comfort multidimensionality”, class 3 “psycho-spiritual comfort”, class 4 “beta pressure”, class 5 “life history and past experiences” and class 6 “intervening variables ”, which address the different signs and symptoms than usual that led the individual to seek help, the way in which he faces the current moment, through psycho-spiritual support and other providers of comfort. CONCLUSION: the study made it possible to know the experiences of patients in palliative care, their senses and spheres of comfort, in addition to proving the applicability of the Theory of Comfort in the context of Palliative Care."

“Introduction: The peripherally inserted central catheter (PICC) is widely used in newborns because it has several advantages when compared to other central vascular access devices and short peripheral intravenous catheters. However, several complications are related to the use of the PICC that can occur from its insertion, through the dwell time and even after its removal. According to the Infusion Nursing Society (2021), complications that may be related to insertion are: inadvertent arterial puncture, cardiac arrhythmias, nerve damage, air embolism, central vascular access device malposition, deep vein thrombosis, infection, phlebitis, infiltration/extravasation and catheter damage. Objective: To analyze the effectiveness of peripherally inserted central catheter insertion techniques in preventing the occurrence of catheter-related complications in newborns. Method: Systematic review of the literature and intervention and network meta-analysis, which the search was performed in seven databases and in the gray literature, including randomized and non-randomized controlled clinical trials that described and compared the PICC insertion techniques and the associated complications. The risk of bias was assessed using Cochrane tools and the certainty of evidence using the Grades of Recommendations Assessment, Development and Evaluation. The meta-analysis was performed using the R statistical program. The process of article selection and data collection, the risk of bias and the certainty of the evidence were performed by two reviewers, independently. Results: Eight studies with a total of 1126 newborns were included and six insertion techniques were identified. Except for anatomical landmarkguided puncture, all techniques significantly reduced tip primary malpositioning of the central vascular access device tip. The intracavitary electrocardiogram reduced arrhythmias, general complications and phlebitis significantly and more effectively, and the technique that used a formula as a way to predict the size of the catheter to be inserted also reduced general complications. Infection, infiltration, secondary malposition of the tip, catheter damage, thrombosis, occlusion and catheter-associated skin injury were not prevented depending on the insertion technique. Conclusion: The intracavitary electrocardiogram and the use of the formula were the most effective techniques in reducing certain complications. As the PICC is essential for hospitalized newborns, more strategies, techniques and technologies should be investigated in order to mitigate the complications related to this catheter in the neonatal population.”

“Introduction: The peripherally inserted central catheter is widely used in critically ill neonates. Adherence to infection control and prevention practices is an important strategy to reduce rates of primary bloodstream infection in neonatal intensive care units. Objective: Descriptive study - To describe the practices of prevention and control of primary bloodstream infection carried out by the nursing team of the neonatal intensive care unit. Retrospective cohort study - To investigate primary bloodstream infection associated with peripherally inserted central catheter in neonatal intensive care units based on indicators of structure, process and results. Method: This is a multi-method study with a sequential approach to quantitative studies: (1) descriptive study - the study participants were nursing professionals and neonates who use the catheter during the hospitalization period. The professionals' data were collected through the completion of a questionnaire via remote and for structure indicator, through asynchronous means of communication channels with the unit's management; (2) retrospective cohort study - newborn data were collected from medical records using a structured instrument. Statistical analysis was descriptive and inferential and considered p-value > 0.050. Data were tabulated in an excel spreadsheet and exported to R (version 4.0.2) for statistical analysis. Result: Thirty nursing professionals participated in the descriptive study, most of whom showed knowledge in accordance with the recommendations above 80% in their responses. A total of 100 neonates were included in the retrospective cohort study. The incidence of primary bloodstream infection was 14%, with significant associations with records of nursing practices and newborn characteristics. Conclusion: Despite the knowledge about the prevention and control practices mentioned by the professionals being in agreement with the recommendations for the most part, it was noticed that the registered practices demonstrated an important factor for the occurrence of infection. ”

“Objective: To analyse the mortality rate of patients who waiting for an ICU bed through court orders according to the priority established by the Federal District Regulation Center and the waiting time for an ICU bed. Material and methods: Retrospective cohort study that included adult patients from the public health system of Distrito Federal, Brazil, who have claimed ICU admission in court from January 2017 to December 2018. Results: The survivors’ fraction of the 1,750 patients have not admitted to the ICU on the first day was 92.1%, however at the end of 14 days the survival rate reduced to 21.6%, considering the total study sample. In this sense, of the patients have admitted to the ICU, 5.5% have not survived the first day compared to 58.9% at the end of the fourteenth day of waiting. Finally, there were 1031 patients have admitted to the ICU bed in total. When waiting time for an ICU bed and the priority and the mortality rate were combined, have been observed that priority I patients were 2.3 times more possibility to die on the second day (OR, 2,304; 95% CI, 1,552-3,418; p < 0.001) and 32 times on the fourteenth day (OR, 32,192; 95% CI, 13,921-74,443; p < 0.001) as the patient have waitedfor an ICU bed. In contrast, priority IV patients have not showed significant variations, showing that on the third day (OR, 1,000; 95% CI, 0.034-29,807; p < 0.001)
and on the fourteenth day (OR, 0.793; 95% CI, 0.310-2442; p < 0001) of waiting for an ICUbed mortality rates were approximately the same. Conclusion: This study has understood that a large number of Priority I patients, who are framed in the legislation and in the several clinical protocols as patients who really need immediate assistance inintensive care, have evolved to death as the days of waiting for a bed of ICU, while the Priority IV patient, recommended by the legislation to be removed from the list for not having benefit or having presented clinical improvement, has had the same chance of death in the first days or at the end of the 14-day waiting period, however its judicialization impairs priority I patient care.”

"Pediatrics health assistance has been worldwide transformed due to the childhood diseases changes. The access to modern and efficient technologies provides worsened and chronic conditions patient’s survival. Institutionalization promotes the necessity of adapting to a new family situation where the child and the family undergo emotional restructuring and the construction of new meanings. The study aimed to know the families with Children ́s Special Health Needs and Complex Chronic Health Conditions experiences in the transition from prolonged de-hospitalization in a Pediatric Intensive Care Unit to a host institution. Data collection was carried out through nine families’ interviews. The research provided the understanding lived by families facing the realities of diagnosis, the challenges of de-hospitalization and institutionalization and also the positive family reorganization after the entire process experienced."

There is limited work in the literature on the seasonality of tuberculosis (TB) in the Southern Hemisphere, making it necessary to fill this knowledge gap for the region.
Investigating the seasonality of this disease may indicate specific risk factors for peak incidence periods that can be controlled if better understood. The study aims to analyze whetherthere is seasonality of TB incidence in Brazil, through an ecological, time-series (ST) study (2001-2019) of cases of the disease. An exploratory analysis of TB seasonality in the Federal District was performed, followed by an investigation of the capitalcities and the Federal District categorized into five groups based on social indicators, disease burden, and Koppen's climate classification, and finally, the SA was analyzed according to the covariates sex, age group, clinical form, and human immunodeficiency virus (HIV) serological status for the country as a whole.
Seasonality was analyzed using formal tests: Friedman test (0.1%) and Kruskal-Wallis test (1%) for stable SA. Moving SA was checked by Friedman's test (5%), and identifiable SA was constructedbased on a combination of the three tests. For each study group, the seasonal range was calculated. RESULTS: In the DF, peaks were observed in April and August, and decreased detection in November and December with an average annual seasonal amplitude of34.0%. TB SA was identified in DF, assuming stability, but mobile seasonality was identified, even when combining the three tests. In all groups of Brazilian capitals, the presence of TB seasonality was identified at the 1% significance level (assumed stability test and Krusall-Wallis, p <0.01); in the combined seasonality test, groups A, D, and E of capitals showed the presence of seasonality; and, probably present, groups B and C. Analysis of Seasonality of TB according to the covariates sex, age group,clinical form, and HIV serology showed identifiable season ality, except among TB cases in which pulmonary and extrapulmonary clinical presentation were observed together. The findings showed that it is a challenge to raise the seasonal factors underlying TB seasonality in the tropical regions of the Southern Hemisphere: climate may not be
the most relevant underlying factor found in TB seasonality, but rather the supply of and/or demand for health services.

"Introduction: The occurrence of urinary symptoms in childhood may be related to significant emotional embarrassment and impaired quality of life. Therefore, nurses need to be able to capture in depth the experience of children with urinary symptoms and their families and propose effective and sensitive interventions, since it is a theme surrounded by stigmas. In this context, the importance of advanced practice nursing is highlighted as specialized knowledge, with the ability to make complex decisions and clinical skills necessary for expanded practice. And primary health care as a promising space for both the nurse's performance with the scope of advanced practice nursing and for the approach of urological symptoms, especially linked to the conservative technique of standard urotherapy as the first line of care. Objective: Develop, through Design Thinking, the prototype of an initiative to qualify nursing professionals to work in the promotion of children's urological health in the context of Advanced Practice Nursing within the scope of Primary Health Care, employing the philosophy Strengths-based nursing and healthcare: The “CUIDE” initiative; and Propose the prototype of the extension course, in the online modality, aimed at nursing students, with the application of Instructional Design strategies, based on the Theory of Symptom Management using the Digital Storytelling technique. Method: It is a study of technological production with a qualitative approach of the descriptive type for the development of a prototype operationalized in two phases. Phase 1: development of the prototype of the CUIDE initiative. Phase 2: elaboration of the prototype of the CUIDE+e extension course. Results: In phase 1, the stage of understanding the problem was based on the survey of national and international bibliography that pointed to the need to qualify nurses for the specific theme; the stage of designing solutions used the brainstorming technique that formulated the CUIDE initiative as a solution; the prototyping stage consisted of developing the objective and goals of the initiative, as well as linking the Strengths-based nursing and healthcare philosophy to the context of child urological care; Finally, the stage of implementing the best solution consisted of detailing the CUIDE initiative, choosing the activity of developing the prototype of the online extension course as the best solution to be implemented. In phase 2, for the analysis, the identification of learning needs was carried out from the conduction of a Focus Group with 14 nursing students analyzed with the referential of the Collective Subject Discourse. In the design, the outline of the course was elaborated; and, finally, in the development, the course details were elaborated. Conclusion: The CUIDE initiative was developed as an innovative solution both for the qualification of nurses in the context of child urology and for the development of advanced practice nursing skills in order to promote these roles in the context of primary health care. The extension course is expected to promote knowledge and development of empathy skills, expanded understanding of the experience of urinary and intestinal symptoms and digital literacy in undergraduate nursing students with a view to strengthening future professional practice in the health context. pediatric urology."

"Introduction: In recent decades, the theme on patient safety has been recurrent in health research, however, the subject is still little explored in Primary Health Care (PHC). Even less explored, evaluating the Culture of Patient Safety (CPS) in PHC is necessary since it favors the implementation of safe practices and the reduction of the occurrence of potential adverse events. Thus, understanding the view of professionals involved in the work process in PHC can stimulate reflection on the practices and efforts made, aiming at improving the safety of care in the context of primary care. Purpose: To evaluate the culture of patient safety among primary health care professionals in a municipality in the Triângulo Mineiro region. To know the state of the art on the subject on screen, an Integrative Literature Review (ILR) was carried out. Method: Scope analysis was performed at the ILR. To evaluate the CPS, an observational, exploratory, quantitative study was conducted. The participants were 407 professionals who are part of the Family Health Strategy teams, according to pre-established inclusion and exclusion criteria, and who agreed to participate in the study by signing the Free and Informed Consent Form. Data were collected between September 2019 and July 2020. The participation took place through the completion of the instrument "Research on Patient Safety Culture for Primary Care". The project was submitted to the Ethics Committee on Research with Human Beings and according to Resolution 466/12 of the National Health Council. For data analysis, there was normal distribution verification, confidence interval estimation, Chi-Square independence test, factor analysis, with evaluation of principal components and Cronbach's alpha. Result: The Integrative Literature Review resulted in 13 articles evaluated, evidencing a positive general assessment regarding the patient's safety culture applying the instrument. The dimension "Teamwork" was the best view, on the other hand, the dimension "Pressure and work rhythm" was pointed out as the worst score. The results of applying the instrument in a municipality of Triângulo Mineiro show a positive general safety culture. The three best-evaluated constructs considered "strengths" of the patient safety culture were "Follow-up of patient care" (90.1%), "Teamwork" (82.6%) and "Exchange of information with other sectors" (82.5%). As weaknesses, the constructs "Support of managers in patient safety" (58.2%) and "Open communication" (54.4%) were presented, being areas that need improvement. Only "Pressure and work rhythm" (27.0%) presented a negative patient safety culture. Conclusion: As in the review, a general positive evaluation of the culture of patient safety by Primary Health Care professionals was indicated by applying the instrument. Nevertheless, the dimension "Pressure and work rhythm" as the worst evaluation is highlighted, demanding improvements in the work processes to ensure the quality of care and patient safety."

"Objective: The study aimed to construct validate the reliability and test the inter and intra-evaluator reliability of an instrument to measure acute radiodermatitis in cancer patients undergoing radiotherapy. Method: this is a methodological study of construction and production of evidence of content validity and reliability of the scale entitled Grading of Acute Radiodermatitis proposed by the LIONCO/UnB group (GRAL). Result: The GRAL scale passed content validation. Fifteen judges from different radiotherapy services in Brazil participated in the study phase. Content validation evaluated the new scale in terms of structure and appearance as well as clarity, pertinence and relevance of the items present in the scale. For analysis, the percentage of partially adequate/adequate judgment (PA/A) among the judges was adopted. The expert committee consisted of four radio-oncologists and eleven nurses. The assessment regarding the structure and appearance of the scale reached an average response for the PA/A items of 87.3%. Regarding the clarity, relevance and relevance of each degree of radiodermatitis described in the scale, all items obtained PA/A above 80.0%. After the adjustments suggested by the judges, the inter and intra-evaluator reliability test of the GRAL scale was carried out. For the analysis of the reliability of the GRAL scale, four professionals were selected by convenience sample, being two nurses and two radio-oncologists, who performed their activities in public radiotherapy services in the Federal District. The professionals evaluated and classified an atlas with images of the different degrees of radiodermatitis, using the GRAL scale, the evaluations took place in two moments (test and retest) with an interval of fifteen days. The percentage of correct values in the agreement of the evaluators' answers was from 76% to a minimum and a maximum of 90% in the first stage of collection (test), for the retest, an agreement
equal to or greater than 80% was observed, therefore, a good stability in the answers. In the agreement analysis used the Kappa test, the value for the inter-evaluator test was from 0.72 to 0.88. In the analysis of agreement for the intra-evaluator test, the Kappa value ranged from 0.77 to 0.88. Conclusion: The GRAL scale was created with the aim of grading radiodermatitis into different ordinal degrees, without overlapping categories. The scale underwent content validation and reliability testing and we can consider that the GRAL scale has evidence of validity and reliability."