"EXPLORING mRNA VACCINES IN HIGH SCHOOL: MOLECULAR BIOLOGY STUDY THROUGH PROJECTBASED LEARNING".
Molecular Biology, Project-Based Learning, Active Learning Strategies, mRNA Vaccines.
In Brazilian high school education, the foundations of molecular biology have been predominantly explored through traditional lectures, with few opportunities for practical activities and dynamics that prioritize active learning. However, given the complexity and rapid advancement of the topics covered and their relevance to students' daily lives, the use of active methods in teaching may be more effective in generating motivation and meaningful learning in students. In this paper, we propose a Didactic Guide that values investigative teaching through the use of the ProjectBased Learning (PBL) method, an active teaching method that places students at the center of the learning process, promoting protagonism and active participation. This methodology involves the development of a group project in which students engage in solving a problem relevant to the school community. The Didactic Guide was created with activities that can assist high school Biology teachers in encouraging students to acquire the skills and competencies outlined in the National Common Curricular Base (BNCC). We used, as an anchor to arouse students' interest and curiosity, a problem that highlighted the importance of mRNA vaccines against COVID-19, through which concepts of molecular biology will be discussed with an emphasis on protein synthesis. In this way, we hope that students will be motivated and understand basic concepts of Molecular Biology and Biotechnology, aiming to contribute to a scientifically enlightened society.