Banca de DEFESA: THALITA QUEIROZ VIEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : THALITA QUEIROZ VIEIRA
DATA : 25/03/2026
HORA: 09:00
LOCAL: Auditório Prof. Dr. Marçal de Oliveira Neto (Hibrido)
TÍTULO:

Explorando os acetatos de adutos de Morita-Baylis-Hillman na reação a resolução cinética enzimática com Cal B e no rearranjo de Ireland-Claisen.

PALAVRAS-CHAVES:

Rearranjo de Ireland-Claisen; adutos Morita-Baylis-Hillman; Resolução Enzimática

PÁGINAS: 149
RESUMO:

Morita-Baylis-Hillman (MBH) adducts are chemical substances obtained by the addition reaction between carbonyl compounds and olefins conjugated with electron-withdrawing groups. The product of this reaction contains an allylic alcohol group, which, when converted into allyl vinyl ethers, can undergo a sigmatropic rearrangement of the [3,3] type, called the Claisen rearrangement. Interest in Claisen rearrangement products has arisen in the chemical community, leading to the development of several studies, resulting in versions of this reaction with variations in reaction conditions, catalysts used, or substrates involved. In this work, the Ireland-Claisen variation was explored, in an unprecedented way, to study the influence of the heteroatom in this reaction, using characterisation techniques such as Nuclear Magnetic Resonance, Infrared Spectroscopy, and Mass Spectrometry. Additionally, enzymatic kinetic resolution assays of MBH adducts prepared from ethyl acrylate and aliphatic and aromatic aldehydes were performed using the CALB enzyme.

MEMBROS DA BANCA:
Externo à Instituição - DIANA DE MENESES SOUZA - IFBA
Interna - 1890721 - ALINE LIMA DE OLIVEIRA PATERNO
Presidente - 2766726 - ANGELO HENRIQUE DE LIRA MACHADO
Interna - 2335199 - TALITA DE ALMEIDA FERNANDES CORREIA