Banca de DEFESA: Marta Rodrigues de Carvalho

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : Marta Rodrigues de Carvalho
DATE: 29/05/2024
TIME: 14:00
LOCAL: Plataforma TEAMS
TITLE:

RESEARCH FOR PRO-THROMBOTIC ANTIBODIES IN PATIENTS WITH POSTINFECTION OR POST-VACCINE COVID-19 STROKE: A CASE-CONTROL STUDY

KEY WORDS:

Stroke; COVID-19; SARS-CoV-2; Epidemiology; Antiphospholipid antibodies.

PAGES: 66
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Introduction: Stroke is one of the main causes of morbidity and mortality in the world. With the advancement of the SARS-CoV-2 pandemic, cases of stroke in patients hospitalized with COVID-19 have accumulated in the scientific literature. Objectives: To investigate the association between exposure to SARS-CoV-2 and the presence of pro thrombotic factors in stroke patients treated in public neurology services of the SUS. Methodology: This is a prospective, hospital-based case-control study. ,. The study is nested within the multicenter case-control titled NeuroCOVID: Association of SARS CoV-2 with the occurrence, prognosis and pathogenesis of cerebrovascular diseases and other neurological manifestations, funded by the Inova Fiocruz Program (Fundação Oswaldo Cruz - Fundo Emergencial de Combate to COVID-19: VPPCB-005-FIO-20-2 22). Results: 148 patients were enrolled for this study at a single center. Among the participants, there was a predominance of female individuals (51.4%, n=76), white ethnicity (29.1%, n=43) and specifically the economically active population (43.9%, n=65). The majority of admitted patients had acute/subacute exposure to SARS-CoV-2 (72.3%, n=107), most of whom were previously vaccinated (80.4%, n=86). Stroke constituted the majority of stroke cases in this study (77%, n=114). The average age was 55.3 years, with a median of 55.5. The average length of stay was 12 days, with a median of 10 days. Conclusion: This study is one of the pioneers in demonstrating clinical epidemiological and laboratory characteristics of patients investigated with stroke. The studied sample presents characteristics similar to those described in other clinical studies. Through the division into acute/subacute exposed, warning exposed and non-exposed, it was possible to draw an overview of severity and outcomes.

COMMITTEE MEMBERS:
Externo à Instituição - AUGUSTO CESAR PENALVA DE OLIVEIRA - EMILIO RIBAS
Presidente - 1156673 - FELIPE VON GLEHN SILVA
Interno - 2095849 - PEDRO SUDBRACK OLIVEIRA
Externo à Instituição - Vinícius Viana Abreu Montanaro - SARAH