Banca de DEFESA: Fabricio da Silva
Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.STUDENT : Fabricio da Silva
DATE: 08/07/2022
TIME: 14:00
LOCAL: Plataforma Teams
TITLE:
Circulatory responses at the onset of isometric exercise: does sex matter?
KEY WORDS:
: blood pressure, systemic vascular resistance, sympathetic cholinergic vasodilation, isometric exercise.
PAGES: 35
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:
The cholinergic vasodilation plays an important role in the blood pressure (BP) and systemic vascular resistance (SVR) responses at the onset of isometric handgrip exercise. Herein, we tested the hypothesis that women present an attenuated fall in SVR and increased pressor response compared to men at the onset of isometric handgrip exercise due to a blunted sympathetic cholinergic vasodilation. Twenty (10 women) young and healthy volunteers (average age: 22 ± 1 years old) were recruited. Participants performed 20s bout of isometric handgrip exercise at 40% of maximal voluntary contraction. Heart rate (HR), mean BP, stroke volume (SV), cardiac output (CO), and SVR responses to exercise were expressed as a change from 10s immediately before the voluntary contraction. Men demonstrated a drop in SVR at 3s (Δ-0.9 ± 0.3 mmHg.L-1 .min), 10s (Δ -1.6 ± 0.4 mmHg.L-1 .min) and 20s (Δ-1.9 ± 0.7 mmHg.L-1 .min) of the onset of isometric exercise, and these responses tend to be attenuated in women (3s: Δ-0.3 ± 0.3 mmHg.L-1 .min; 10s: Δ-1.2 ± 0.4 mmHg.L-1 .min; 20s: Δ-0.6 ± 0.5 mmHg.L-1 .min; P=0.131). While men present a typical exercise-evoked biphasic mean BP response, women show a progressive increase in BP at the onset of exercise. There are no sex differences in HR, SV and CO responses to exercise, which all increased progressively over the 20s of handgrip bout. These findings demonstrated a lack of sex differences in SVR and BP responses at the onset of isometric handgrip exercise, suggesting that the sympathetic cholinergic vasodilation contribution to circulatory responses at the beginning of exercise is irrespective of sex.
BANKING MEMBERS:
Presidente - 2101604 - LAURO CASQUEIRO VIANNA
Externo ao Programa - 1794344 - RICARDO MORENO LIMA
Externo ao Programa - 396869 - RICARDO JACO DE OLIVEIRA
Externo à Instituição - ANDRE LUIZ DA SILVA TEIXEIRA - UOG