Banca de DEFESA: RAFAEL DE NEGREIROS BOTAN

CREATION OF A DATABASE WITH REAL-TIME RESULTS OF GLOBAL SURVIVAL OF BREAST CANCER PATIENTS

Breast cancer. Oncology. Survival Data Network. Information systems.

Introduction. Breast cancer globally represents one of the leading causes of mortality among women, which underscores the need for effective pathways for the treatment of individuals with this disease. The collection, storage, and processing of survival data with the interest of understanding the correlation between treatment and survival demands time from researchers and institutions. Objective. The present study was designed to create an innovative real-time survival data network, with the aim of correlating survival time with used treatments, with the purpose of generating hypotheses for future prospective studies regarding the survival benefits of treatment in different clinical, social, and geographic contexts. Methods: After defining the data conventionally considered as crucial in the treatment of breast cancer, a data network was designed that returns to the physician the overall survival, progression-free survival, and event-free survival in real time. The criteria for each survival metric were defined and a real-time chart was generated where all survivals are represented and, when combined, result in the overall survival. Results: With free and simple registration, the network was created and allows access to any Brazilian oncologist. Patient entry is fully parameterized, allowing the quick and safe input of information about the disease and treatment. The physician can access patient data in real time and thus can compare it with results from the literature, especially survival data, using advanced filters. Consent for the submission of information is obtained electronically from the patient, also in real time, from an email address or phone. Conclusion: This data network is feasible and can be a tool of interest in research institutions, particularly as a screening for larger studies.