Banca de DEFESA: Beatriz Rodrigues de Barcelos

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : Beatriz Rodrigues de Barcelos
DATE: 21/06/2024
TIME: 14:00
LOCAL: On line (Teams)
TITLE:

Analysis of the use of repellents against ticks of the species Amblyomma sculptum (ACARI: IXODIDAE) transmitters of spotted fever

KEY WORDS:

tick, spotted fever, Amblyomma sculptum, repellent

PAGES: 55
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

*Resumo em inglês: Brazilian Spotted Fever, acquired through the bite of the infected star tick (Amblyomma sculptum), can become fatal if not properly treated. In the Brazilian context, there is a lack of information regarding the efficacy of repellents against A. sculptum. Therefore, the purpose of the experiments is to evaluate the chemical repellency of products containing the compounds DEET, IR3535, and Icaridin, used in combating this tick, with the aim of verifying the safety of these products. Six commercial repellents registered with the National Health Surveillance Agency (ANVISA) were chosen for the experiment: OFF!®, Repelex®, Johnson®, Henlau®, Exposis®, and SBP®, with two of each mentioned compound. Three bioassays were conducted to assess tick behavior: i) Filter Paper Bioassay, ii) Finger Tip Bioassay, and iii) Field Test. In all tests conducted, the formulations demonstrated high repellent activity, showing significant differences (p<0.05) compared to the control group. In the Finger Tip Bioassay and Field Test, the most effective products were OFF!®, Repelex®, and Exposis®, as they performed better in the filter paper assay. In the Finger Tip evaluation, the DEET base repelled a greater number of ticks compared to Icaridin. In the Field Test, there was no significant difference between the Icaridin and DEET bases, both differing from the control (p<0.05). OFF!® showed the highest repellent percentage (100%), followed by Repelex® (96.8%) and Exposis® (93.1%), considering the two-hour period of the field bioassay. Confirmation of the effectiveness of these commercial repellents against A. sculptum, as presented in this study, is of paramount importance, given that this tick is the primary ectoparasite of humans and can transmit Rickettsia rickettsii when infected. Furthermore, the effectiveness of these repellents against other tick species that parasitize humans can also be explored.

COMMITTEE MEMBERS:
Externa à Instituição - MORGANA MARIA ARCANJO BRUNO - UCB
Interno - 1947457 - LEONARDO PETRUS DA SILVA PAZ
Presidente - 1974062 - MARCOS TAKASHI OBARA
Externo à Instituição - STEFAN VILGES DE OLIVEIRA - UFU
Interna - 1974065 - VANESSA RESENDE NOGUEIRA CRUVINEL