ANALYSIS OF NON-LINEAR HEART RATE VARIABILITY AS AN INDICATOR OF CARDIOVASCULAR RISK IN PEOPLE LIVING WITH HIV: IMPACT ON PHYSIOTHERAPEUTIC INTERVENTIONS
physical exercise; HIV; heart rate variability
Introduction: The human immunodeficiency virus, clinically known as HIV, is the virus responsible for the deficiency of the immune system of its carrier, and the exacerbation of the condition triggers acquired immunodeficiency syndrome. Objectives: To propose non-linear heart rate variability as an indicator of cardiovascular risk in people living with HIV, with modulation of these variables through physiotherapeutic interventions. Materials and Methods: This is a longitudinal experimental study of the randomized clinical trial type, with a sample composed of individuals of both sexes and genders aged between 18 and 60 years. For the development of the research, the sample will be composed of four groups, three groups of people with human immunodeficiency, described as the acute infection group, the clinical latency group and the severe infection group, and the fourth group described as the control group composed of non-carrier individuals. Four procedures will be performed before and after the physiotherapeutic intervention, these being heart rate variability (in supine, sitting, standing positions and during the 6-minute walk test), electrocardiogram, surface electromyography (from three points on the upper limbs and three points on the lower limbs), cardiopulmonary test, and questionnaires on quality of life and level of physical activity. Partial results: 42 volunteers have been analyzed so far, 21 individuals living with HIV (5 cisgender women, 1 transgender woman, 15 cisgender men) and 21 individuals making up the control group (same composition). Of the groups living with HIV, 2 volunteers have severe infection, and 19 volunteers are in clinical latency. All groups were evaluated by IPAQ and are matched in terms of fitness (3 active, 18 sedentary in each group). Volunteers with HIV, regardless of their level of conditioning and phase of infection, had lower heart rate variability compared to the control group. However, it was observed that active participants had better values compared to sedentary participants. Regarding musculoskeletal findings, volunteers with various infections showed considerable reductions in contractility in the lower and upper limbs, so that active individuals had lower Root Mean Square (RMS) compared to the control group. It was established through a systematic review and meta-analysis of the parameters for performing physical exercises in the population living with HIV.