Banca de DEFESA: Pollyanna Barbosa Farias Barros

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : Pollyanna Barbosa Farias Barros
DATE: 16/01/2023
TIME: 14:00
LOCAL: Plataforma Teams
TITLE:

Graft survival assessment of patients followed by the renal transplant service at the University Hospital of Brasília

KEY WORDS:

Kidney transplantation, survival analysis, Risk factors

PAGES: 39
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

Kidney transplantation (TX) is the treatment that offers the best prognosis and quality of life for patients with end-stage chronic kidney disease. However, graft survival time depends on factors from the donor, organ conservation, recipient and post-TX care.These factors may have different relevance depending on the TX center, its criteria for organ acceptance and subsequent outpatient follow-up. Predictive indexes for graft survival are based on American and European populations, and may not replicate the Brazilian reality. Objective: To analyze the predictive factors of renal graft survival censored for death in patients followed by the transplant service of the Hospital Universitário de Brasília. Methodology: observational, historical cohort study. A retrospective analysis of the medical records of kidney transplant patients, over 18 years old and of both sexes, will be carried out, followed by the TX service of the HUB, since 2006, the year of implantation. Patients with loss of follow-up and, consequently, without information will be excluded. The data will be transferred to a data management platform called Research Electronic Data Capture (REDCap). Kaplan-Meier survival analysis will be performed and compared with the variables related to the donor, recipient and post-transplantation care through multivariate analysis. Graft failure will be considered when the patient again needs hemodialysis or a new kidney transplant. Deaths with a functioning kidney will be censored. Based on these results, a predictive model will be proposed using multivariate regression. The project was approved by the Human Research Ethics Committee. Partial results: The structure of the forms for collecting the variables that will be extracted from the medical records of the patients under study in the database on the REDCap platform was built.

BANKING MEMBERS:
Externo à Instituição - IGOR DENIZARDE BACELAR MARQUES - UFPI
Presidente - 2102264 - DAYANI GALATO
Externo à Instituição - FRANCISCO DE ASSIS ROCHA NEVES - UnB
Interna - 1707017 - MANI INDIANA FUNEZ