Banca de QUALIFICAÇÃO: Danilo César Mota Martins

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : Danilo César Mota Martins
DATE: 29/08/2022
TIME: 08:00
LOCAL: Plataforma Teams
TITLE:

Microbial profile, immune response and treatment protocols for odontogenic infections at Instituto Hospital de Base do Distrito Federal

KEY WORDS:

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PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

Severe odontogenic infections are considered a major public health problem, pose a risk to patients and have likely become a significant economic burden for the public health system. Incorrect or delayed treatment often leads to serious complications such as compromised airways, septicemia, and even death. The infection spread depends on local and systemic factors of the host and the virulence of the agent. Thus, this project aims to firstly evaluate the clinical data of patients diagnosed with infections of odontogenic origin, followed by the evaluation of the microbial pattern, immune response, and treatment protocols for these infections at the Instituto Hospital de Base do Distrito Federal (IHBASE). In view of the above, clinical data were collected from the IHBASE electronic medical records, including signs, symptoms, evolution of the condition, and serum data. Subsequently, during the treatment procedure, exudate was collected from abscesses that required drainage, followed by extraction of microbial DNA for future analysis of the immunological profile and microbial pattern. Additionally, treatment protocols (local and systemic) will be analyzed, with a main focus on the antibiotics used. All these data will be correlated with each other and the factors contributing to the clinical outcome of the infection will be analyzed. An analysis of the amount of hospitalization days required for patient homeostasis was also accounted. In this way, the project aims to establish treatment protocols that will allow for a shorter treatment time, a lower rate of microbial resistance development and lower public investment expenditure for these treatments. The knowledge acquired during the development of this project has a direct impact on the clinical management of these patients, increasing the population's quality of life.

BANKING MEMBERS:
Externa à Instituição - STELLA MARIS DE FREITAS LIMA - UCB
Externo à Instituição - ANTÔNIO PAULINO RIBEIRO SOBRINHO - UFMG
Externa ao Programa - 1225359 - ERICA NEGRINI LIA
Presidente - 768.449.191-15 - TAIA MARIA BERTO REZENDE - UFMG