Banca de DEFESA: LETÍCIA DE ANDRADE ZAGATTO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LETÍCIA DE ANDRADE ZAGATTO
DATE: 09/08/2024
TIME: 09:00
LOCAL: Plataforma Teams
TITLE:

Calcified carotid atheromas and osteoporosis markers in panoramic radiographs: a comparative study

KEY WORDS:

calcified carotid artery atheroma; osteoporosis; mandibular cortical index; cardiovascular disease; screening; public health

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

“ With the aging of the global population, there is an increase in the incidence of chronic diseases such as osteoporosis and strokes. These diseases pose significant challenges for public health due to their morbidity, mortality, and the high costs associated with hospitalizations. Dentists can assist in opportunistic screening of patients at higher risk for these diseases through panoramic radiographs, by identifying calcified carotid atheromas and resorption in the lower cortical bone of the mandible. These radiographs are routinely performed in daily clinical practice. The identification of calcified carotid atheromas and resorption in the lower cortical bone of the mandible can be useful tools in identifying patients at higher risk for cardiovascular diseases and osteoporosis, respectively. Studies suggest the concomitant appearance of these alterations in many patients and that the diseases may have similar pathophysiological mechanisms. In this context, the general objective of this study is to investigate the relationship between the presence of calcified carotid atheromas and erosion in the lower cortical bone of the mandible in panoramic radiographs. Specifically, the study determined the prevalence of calcified carotid atheromas in panoramic radiographs of patients treated at the University Hospital of Brasília. This is a cross-sectional study. Initially, the database of the University Hospital of Brasília, composed of 19,205 radiographs, was evaluated. The selection process for panoramic images suspected of having calcified carotid atheromas was conducted by a dentist specialized and trained in identifying this condition in panoramic radiographs. Doubtful cases were reviewed, and disagreements resolved with the help of a second dental radiology specialist with 25 years of experience in the field. From this, a database of panoramic radiographs suspected of having calcified carotid atheromas was created. The prevalence of these calcifications was calculated as the ratio of radiographs with calcifications to the total number of radiographs in the HUB database. From the initially analyzed database of patients with atheromas, panoramic radiographs without atheromas were selected, forming a control group matched by age to the group with atheromas. The dentist was also trained to evaluate the integrity of the mandibular cortical bone, using the following classification: C1 - normal cortical, C2 - cortical with signs of endosteal surface resorption, and C3 - cortical with severe erosions. The relationship between the presence of atheroma and cortical classification was analyzed using the chi-square test and a binomial logistic regression model. In total, 272 panoramic radiographs showed calcifications (1.4% of the studied population). A total of 422 images compatible with calcified carotid atheromas were identified, with 122 being unilateral (63 on the right side and 59 on the left side) and 150 bilateral. There was a significant difference in the percentage of patients with cortical erosion in the group with atheromas (p<0.001). There was no statistically significant difference between sides or between types (unilateral or bilateral) in the group with atheromas (p>0.05). In a binomial logistic regression model, it was found that individuals with cortical erosion were twice as likely to have calcified carotid atheroma compared to those without this condition. This study demonstrated a possible relationship between the presence of calcified carotid atheromas and erosions in the lower cortical bone of the mandible. Therefore, panoramic radiography can be a useful tool in identifying atheromas and osteoporosis, two chronic conditions with significant impact on patient health. The prevalence of atheromas found was similar to that reported in the literature.”

COMMITTEE MEMBERS:
Presidente - 3437282 - ANDRE FERREIRA LEITE
Externa ao Programa - 1700013 - CARLA RUFFEIL MOREIRA MESQUITA - nullExterna à Instituição - Danielle Leal Vieira - HFA
Interna - 2315081 - NILCE SANTOS DE MELO