“The Biological Potential of AH Plus Bioceramic Endodontic Cement and Calcium Silicate-Based Repair Cements”
“Silicate Cement. Dental Cements. Root Canal Obturation”
“Cements based on calcium silicate are considered materials of choice for the reparative treatment of root perforations and apical surgeries. Over the years, these materials have been refined, culminating in the establishment of bioceramic cements for such treatments. Their bioactive potential, biocompatibility, and moisture tolerance also qualify them as options for filling the root canal system. The aim of this study was to evaluate the biological properties of reparative bioceramic cements in human osteoblastic cell culture, as well as bioceramic filling cements in human osteoblastic and pulp cell cultures. The study assessed the properties and indications of bioceramic cements in endodontics, as well as their use as reparative cements in regenerative treatments. A literature review was also conducted with current research that contributed to this work. Additionally, an ebook was published on a recently launched filling cement, the AH Plus® Bioceramic Sealer. A literature review was performed with more recent articles on its biological and physicochemical properties, as well as its composition. Three successful clinical cases were described using the AH Plus® Bioceramic Sealer as a filling cement. An analysis was presented on filling cements that may come into direct contact with different types of cells and cause adverse reactions or stimulate mineralization. In the study, cell viability (MTT), proliferation area (Wound Healing Assay), and mineralization potential (calcium deposition using Alizarin Red staining) of human pulp and osteoblastic cells were compared after exposure to AH Plus® Bioceramic, Bio-C® Sealer, NeoMTA Plus®, and MTA-FILLAPEX®. Furthermore, a comparative study was described on the potential of bioceramic reparative cements to induce mineralization in cultures of human osteoblast-type cells (Saos-2). The objective was to evaluate the bioactivity of two prominent bioceramic reparative cements in Brazil, Bio-C® Repair and PBS HP®, which were made available with the promise of superior biological properties compared to conventional cements”