Banca de DEFESA: ANA LUIZA MAGALHÃES DE SOUZA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ANA LUIZA MAGALHÃES DE SOUZA
DATE: 30/04/2025
TIME: 09:00
LOCAL: Plataforma Teams
TITLE:

Oral health-related quality of life in people with type 2 Diabetes: a cross-sectional study

KEY WORDS:

Diabetes; Quality of Life; Oral Health; OHIP

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

“Objectives: This study aimed to compare the oral health-related quality of life (OHRQoL) of individuals with and without type 2 diabetes mellitus (T2D) and to identify factors associated with low OHRQoL among individuals with T2D. Additionally, the study sought to validate the ultra-short version of the Oral Health Impact Profile (OHIP-5) for Brazilian Portuguese. Methods: A cross-sectional study was conducted with dentate adults (>35 years) with and without T2D. Blood and salivary flow at rest samples were collected, and a complete periodontal examination performed. Sociodemographic data and the OHIP-5 questionnaires were administered. Comparisons between individuals with and without T2D were made using chi-square or Fisher's exact tests for nominal and categorical variables and the Mann-Whitney test for continuous variables, following the Shapiro-Wilk normality test. To identify factors associated with OHRQoL in individuals with T2D, simple linear regressions were performed for each independent variable, and multiple linear regression was conducted by including variables with p < 0.20 in the simple linear regression. For the validation of OHIP-5, Exploratory Structural Equation Modeling (ESEM) with Maximum Likelihood (ML) estimation was used. Model fit quality was assessed by the Comparative Fit Index (CFI), the Root Mean Square Error of Approximation (RMSEA), and the Standardized Root Mean Square Residual (SRMR). The significance level adopted was 5%. Statistical analyses were performed using SPSS software, version 26.0. Results: The study included 168 individuals, 87 with T2D (mean age 54.62 ± 10.51 years) and 75 without T2D (mean age 52.68 ± 10.68 years) (p = 0.169). A statistically significant difference was found between groups in the number of remaining teeth (with T2D = 20.62 ± 6.78 and without T2D = 22.5 ± 6.66, p = 0.032), number of medications (polypharmacy) (with T2D = 4.34 ± 2.74 and without T2D = 1.03 ± 1.42, p < 0.0001); OHIP-5 Sum (with T2D = 6.46 ± 4.83 and without T2D = 4.63 ± 4.06, p = 0.012), OHIP-5 mean (with T2D = 1.29 ± 0.97 and without T2D = 0.92 ± 0.81, p = 0.012) and OHIP5 discomfort (with T2D = 1.78 ± 1.63 and without T2D= 1.15 ± 1.36, p = 0.019). The multiple linear regression conducted to predict Quality of Life (OHIP Sum) included the variables "Sex," "Age," "Stopped taking care of Oral Health due to cost," "Prosthesis Use," "Diabetes Duration," "Number of teeth," "Fasting Glucose," "C-reactive Protein," "BMI," and "Periodontitis." The multiple regression model resulted in Z(10, 83) = 5.225, p < 0.0005, R² = 0.39, adjusted R² = 0.31. The OHIP-5 instrument validation test showed better psychometric properties for the group with T2D (CFI = 1.0; RMSEA < 0.0001; SRMR = 0.15) than for the group without T2D (CFI = 0.972; RMSEA = 0.074; SRMR = 0.056). Conclusions: OHIP-5 showed adequate psychometric properties for assessing OHRQoL among individuals with T2D. Individuals with T2DM had worse OHRQoL compared to those without T2DM. Factors associated with low OHRQoL among individuals with T2DM were diabetes duration, number of remaining teeth, BMI, and periodontitis.

COMMITTEE MEMBERS:
Externa à Instituição - MARIA CYNÉSIA MEDEIROS DE BARROS - UFRJ
Externa ao Programa - 1135613 - BRUNA FRIZON GREGGIANIN - nullPresidente - 1889805 - CRISTINE MIRON STEFANI
Interna - 3249597 - RAYSSA FERREIRA ZANATTA