EFFECT OF OZONE THERAPY ON THE QUALITY OF LIFE OF PATIENTS WITH XEROSTOMIA AND HYPOSALIVATION POST-RADIOTHERAPY OF THE HEAD AND NECK: A CROSS-CROSS STUDY
ozone therapy, dentistry, xerostomia
Every year, more than half a million patients worldwide are diagnosed with head and neck cancer and, of these cases, approximately 75% are treated with radiotherapy. This frequent radiation affects the glandular tissues in the region, leading to the appearance of xerostomia. This saliva deficiency can cause several changes such as pain, susceptibility to ulcerations, dysphagia, dysphonia, among others, which affects the quality of life of these patients, with negative impacts both emotionally and mentally. Ozone therapy has proven to be very effective in several areas of medicine, in particular due to its antioxidant characteristic that acts to reduce the oxidative process, as well as increase vascularization and the immune system. The objective of this study was to evaluate the quality of life of patients with xerostomia after head and neck radiotherapy before and after treatment with ozonated gas. The study was submitted to the Research Ethics Committee and began execution after approval. 8 patients were evaluated and the Related Quality of Life Scale (XeQoLS) questionnaire was applied, of which 6 were male and 2 were female, the average score before treatment was around 66.75 and after ozone treatment it was 32,25, all patients claimed improvement in salivation after treatment. It can be concluded that the ozonized gas was effective in improving the salivation of the patients studied, improving their quality of life.