"EFFECT OF OZONIZED GEL ON THE CONTROL OF PAIN, EDEMA AND TRISM IN PATIENTS UNDERGOING LOWER THIRD-PARTY MOLAR EXTRACTIONS: A SPLITMOUTH RANDOMIZED CLINICAL TRIAL"
"ozone therapy, dentistry, edema, trismus, pain"
"Ozone is a variant gas derived from oxygen. In dentistry, ozone has shown promise due to its biological characteristics such as antimicrobial effect, analgesic action, anti-inflammatory property and aid in tissue repair. General objective: to verify if the use of ozonized gel brings difference in the postoperative period of extraction of lower third molars in terms of pain, edema and trismus. The study will be a double-blind, split-mouth, randomized clinical trial. The study was submitted to the Research Ethics Committee and its execution began after its approval. Surgeries were performed to extract the lower third molars bilaterally with a minimum interval of three weeks between them, with ozone gel therapy being performed on one side only. Conventional analgesia was administered postoperatively in both groups. Participants answered pain-related questions by completing the VAS Pain Scale and noted the amount of analgesics administered on days 0 (surgery day), 1, 3 and 7 (postoperative days). On the same days, a calibrated examiner measured the edema (with the aid of a flexible measuring tape) and the mouth opening (with a digital caliper). Through statistical analysis, it was evaluated whether the use of ozonized gel brings a difference in the postoperative period in lower third molar extraction surgeries."