Banca de DEFESA: Carina Machado Orlandi da Veiga Jardim

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : Carina Machado Orlandi da Veiga Jardim
DATE: 28/04/2023
TIME: 14:00
LOCAL: Plataforma Teams
TITLE:

"Lesions in the oral cavity during hospitalization due to COVID-19, a Systematic Review"

KEY WORDS:

"Coronavirus, Oral Manifestations,Hospitalized Patients"

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

"coronavirus, popularly known as COVID-19, has created a challenging global crisis in health systems. Most cases are asymptomatic or trigger mild symptoms, such as a mild flu, but more severe responses can develop, such as fulminant pneumonia. During the COVID-19 pandemic, the severe health complications caused by SARS-CoV-2 increases the length of stay in the Intensive Care Unit (ICU), and increases the type and number of manifestations already found in the hospital environment. Many oral symptoms related to COVID-19 have already been described in the literature, however, there is a shortage of oral signs triggered by this infection. The objective of this Systematic Review is to assess the prevalence of oral cavity lesions in adult patients diagnosed with COVID-19 hospitalized at the infirmary or ICU. Methodology: A search was carried out in PUBMED/Medline, Embase, LILACS, Web of Science, Scopus, Livivo, Google Scholar, Open Gray and Proquest, in addition to a manual search of the reference list of included studies. For the research of studies, a combination of descriptors and free terms for “coronavirus”, “oral manifestations” and “hospitalized patients” were used. For selection and management of references, EndNoteBasic® and Rayyan applications were used. Studies published between 2020 and 2022 (period corresponding to the pandemic) were selected, which obligatorily included adult patients, over 18 years old, diagnosed with COVID-19, admitted to the infirmary or ICU, who had oral lesions. The methodological quality was analyzed using the tools in the Joana Briggs Institute (JBI) manual. The extracted data were organized in tables, and a rigorous narrative synthesis was carried out. Results: A total of 3,952 studies were found, leaving 79 for full reading, and 24 studies were included, namely: six case reports, four case series, three cohort studies, ten cross-sectional studies and one case control, developed in ten countries, being a single study without reporting the country of performance. In most studies, the type of test used for the diagnosis of COVID-19 was reported, as well as the type of ventilation used by the patient during hospitalization. All 24 studies reported the location and types of lesions, thus the decreasing prevalence of the types of lesions are candidiasis (11.42%), followed by nonspecific ulcerated lesions (9.5%), nonspecific oral bleeding (4.30%) and viral lesions (2.70%). The location of the lesions is described as lips, tongue, palate and gums. Conclusion: Patients hospitalized in a hospital environment develop lesions in the oral cavity, as well as patients diagnosed with COVID-19, with fungal lesions being the most prevalent both in hospital patients and in patients diagnosed with COVID-19. However, a high level of heterogeneity in the studies and applied methodologies, as well as the lack of standardization of the location and types of injuries, limited the comparison of results and outcomes. Thus, there is a need for more standardized studies, which therefore allow comparative analysis."

BANKING MEMBERS:
Presidente - 3475960 - PAULO TADEU DE SOUZA FIGUEIREDO
Interna - 2315081 - NILCE SANTOS DE MELO
Externa ao Programa - 1700013 - CARLA RUFFEIL MOREIRA MESQUITA
Externo à Instituição - Alexandre Franco Miranda - UCB