Banca de DEFESA: Camilla de Miranda Ribeiro

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : Camilla de Miranda Ribeiro
DATE: 10/10/2023
TIME: 14:00
LOCAL: A definir
TITLE:

“CHARACTERIZATION OF PNEUMOCOCCAL MENINGITIS CASES AND DEATHS AND IMPACT OF THE 10-VALENT PNEUMOCOCCAL CONJUGATE VACCINE IN BRAZIL, 2007 TO 2019.”

KEY WORDS:

“Streptococcus pneumoniae; Pneumococcal Meningitis; Pneumococcal Vaccines”.

PAGES: 1000
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

“Introduction: To characterize the epidemiological profile of cases of Pneumococcal Meningitis (PM) in the pre- and post-implantation periods of the 10-valent pneumococcal vaccine (Conjugate) (PCV-10) in Brazil. Methods: A descriptive study of PM cases registered in the Notifiable Diseases Information System (Sinan) between 2007-2019 was carried out. The year 2010 (year of introduction of PCV-10) was excluded. The following periods were defined: pre-vaccination (2007-2019) and post-vaccination (2011 to 2013), (2014 to 2016) (2017 to 2019). Results: In Brazil, there were 12,105 cases of PM between 2007-2009 (n=3,158; 26.1%), 2011-2013 (n= 3,246; 26.8%), 2014-2016 (n= 2,709; 22.4 %) and 2017-2019 (n= 2,992;24.7%). There was a predominance of males in the analyzed period. There was a reduction in cases in children < 01 year of age, in the three post-vaccine three-year periods (11.5%, 10.6% and 8.2%, respectively). In the age group ≥ 60 years old, the proportion of cases corresponded to 9.4% before vaccination. In the three post-vaccination periods, it corresponded to 13.4%, 16.4% and 19.7%, respectively. In these age groups, similar changes were observed in relation to deaths. The lethality rate was approximately 29.0%, even after the introduction of the vaccine. In the pre- and post-vaccination period, there were cases in the 27 Federative Units (FU), concentrated in the Southeast (60.9%), and in this region there was an increase in the average number of cases in the three post-vaccination periods (n =1,870) in relation to the pre-vaccination period (n=1,764). Conclusion: There were changes in the age group distribution after the use of PCV-10 and a slight increase in cases in the Southeast, suggesting that vaccine coverage and serotypes not included in the vaccine may be associated with this fact.”

COMMITTEE MEMBERS:
Externa à Instituição - CAMILE DE MORAES - MS
Presidente - 1225317 - EDGAR MERCHAN HAMANN
Interna - 484663 - ELISABETH CARMEN DUARTE