Banca de DEFESA: Jeanne Fernandes Pereira

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : Jeanne Fernandes Pereira
DATE: 06/06/2023
TIME: 09:00
LOCAL: Remota via Microsoft Teams
TITLE:

COVID-19 influence on the leprosy treatment adherence in a Brazilian public hospital

KEY WORDS:

leprosy, treatment adherence, adverse drug reaction and COVID-19

PAGES: 110
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Leprosy is considered a serious public health problem worldwide. It is a disease caused by Mycobacterium leprae with high potential to induce incapacitation. Low treatment adherence is responsible for transmission outbreaks, incomplete cure, therapeutic resistance and increased patient´s irreversible damage. During Covid-19 pandemic, started on March 11 of 2020, according to the World Health Organization, several patients did avoid to seek public health services due to social isolation measures. Thus, the retrospective, observational study aimed to evaluate treatment adherence in patients with leprosy followed at the University Hospital of Brasília-DF before and during the Covid-19 pandemic. The study included 71 patients, older than 18 years old, who started and completed leprosy treatment between January 2018 and December 2021. Sociodemographic and clinical data was collected from patient´s monitoring forms and electronic medical records. Adherence to treatment was measured based on the percentage of drug refilled at the Dermatology outpatient clinic of HUB in first 6 months for PB patients and the first 12 months for MB patients. Adherent patients were considered those who used at least 80% of the total number of pills recommended for leprosy treatment. The study showed that 90.1% of the patients had adherence to the treatment, 53.5% were female, 71,8% were brown and the age mean were 44.5±12.9 years. Comparing adherent and non-adherent patient´s groups regarding sex, age, race, previous treatment, adverse reactions, polypharmacy, single treatment, and leprosy episode, we did not observe any statistical difference. But, comparing these groups regarding the presence of comorbidity, we observed a higher frequency of comorbidity in the non-adherent group (85.7%) than in the adherent group (32.8%), with p value = 0.0105. We also observe that patients that receive the leprosys treatment during the Covid-19 pandemic had higher tendency for non-adherence, in comparison with those treated without the influence of Covid-19. This study showed that patients with comorbidities are more non-adherent, and also shown that pandemic did not have significative influence on patient´s treatment for leprosy, despite the tendency of higher non-adherence in patients treated during the Covid-19 pandemic.  Those facts demonstrate that it is necessary implement public policies to help health professionals to maintain the existing care and assume co-responsibility for those patients who tend not to accept the disease and treatment, avoiding the evolution of the disease, as well as its possible complications and streaming.

BANKING MEMBERS:
Presidente - 3041905 - INGRID FERREIRA METZGER
Interna - 1865506 - MICHELINE MARIE MILWARD DE AZEVEDO MEINERS
Externo ao Programa - 2676451 - CIRO MARTINS GOMES
Externo à Instituição - GUSTAVO LAINE DE ARAUJO OLIVEIRA - MS