Banca de DEFESA: Maria Isabella Claudino Haslett

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : Maria Isabella Claudino Haslett
DATE: 12/07/2023
TIME: 14:00
LOCAL: Virtual (teams)
TITLE:

Outpatient syndromic surveillance for urban respiratory infectious agents and arboviruses transmitted by Aedes aegypti, in vulnerable population of the Federal District, 2022

KEY WORDS:

Syndromic Surveillance; Infectious Disease; Respiratory Diseases; Arboviruses; Primary Health Care.

PAGES: 235
BIG AREA: Ciências da Saúde
AREA: Medicina
SUBÁREA: Clínica Médica
SPECIALTY: Doenças Infecciosas e Parasitárias
SUMMARY:

Introduction: With the Covid-19 pandemic, we realized the need to revisit our traditional surveillance models, shifting away from an epidemiological surveillance conception focused on detection, to a syndromic approach, which enables real-time knowledge, timely response, and systematic monitoring of the population and environment health, and human-environment interaction. The study aimed to describe the epidemiological findings of population-based syndromic surveillance for respiratory infectious agents and urban arboviruses transmitted by Aedes aegypti in primary healthcare, in a socioenvironmental vulnerable area in the Federal District. Methods: We set up a descriptive study with people living at SCIA/Estrutural, with > 1 year old, who went to the health unit for medical assistance between January-December/2022. On free demand, suspected cases were those who reported acute or referred febrile manifestation, with one or more illness-related signs and symptoms. Participants were interviewed in the health unit with a structured online form. Biological samples were collected for diagnosis - nasopharyngeal swabs for respiratory diagnosis (RT-PCR), and blood for arboviruses diagnosis (RT-PCR/serology). All participants signed the consent form. Results: 987 participants were enrolled in the study: 63.0% (622/987) were female; median age was 30 years (IQR: 24-42); 60.9% (601/987) self-declared Hispanic, and 39.8% (393/987) with high school education. From nasopharyngeal samples (n=985), SARS-CoV-2 was detected in 20.4% (201/985); among the negative ones for this analysis (n=784), in 42.6% (334/784) Influenza A serotypes were detected; 26.3% (206/784) had Haemophilus influenzae, and 21.7% (170/784) Human Rhinovirus. Of blood samples (n=878), 9.2% (81/878) had some arbovirus detection: 58.0% (47/81) DENV; 30.9% (25/81) CHIKV, and 2.5% (2/81) ZIKV. Co-detections between arboviruses occurred in 8.6% (7/81) of the cases. Regardless of the etiological agent, the most frequent signs and symptoms for confirmed cases were headache, cough, coryza, sore throat, and myalgia.  Overall, 27.4% (215/784) remained undiagnosed. No serious cases or deaths were detected. Conclusions: The syndromic approach and laboratory diagnosis collaborated with surveillance sensitivity and opportunity, at the local level, and offered an accurate diagnosis for the population. Demonstrated that continuous and systematic data monitoring enables more timely interventions, mitigating the impact on the populations and on the health system. We recommend that the syndromic approach in health surveillance become a priority agenda for public health so that it can become a health policy and no longer an individual/specific initiative.

COMMITTEE MEMBERS:
Presidente - 1961891 - WILDO NAVEGANTES DE ARAUJO
Interno - 1974062 - MARCOS TAKASHI OBARA
Interno - 1773755 - WALTER MASSA RAMALHO
Externo à Instituição - Jadher Pércio - MS